Index

Handout for the Department Meeting 19900306

ahaptoglobinaemia

1. haptoglobin
   (ref.1) Merck Index. 9th edition.
2. first report = genetic hypothesis
   (ref.2) Allison, A.C. et al. (1958) Haptoglobin types in British, Spanish Basque and Nigerian African populations. Nature, 181:824-825.
3. genetic hypothesis suggested in American Negroes
   (ref.3) Giblett, E.R. (1959) Haptoglobin Types in American Negroes. Nature, 183:192-193.
4. malarial hypothesis suggested in Africans
   (ref.4) Trape, J.F. et al. (1985) Malaria, cause of ahaptoglobinaemia in Africans. Trans. R. Soc. Trop. Med. Hyg., 79:430-434.
   (ref.5) Trape, J.F. and Fribourg-Blanc, A. (1988) Ahaptoglobinemia in African populations and its relation to malaria endemicity. American Journal of Epidemiology, 127(6):1282-1288.
5. malarial hypothesis also suggested in Melanesians
   (ref.6) Curtain, C.C. et al. (1965) Haptoglobins and transferrins in Melanesia: relation to hemoglobin, serum haptoglobin and serum iron levels in population groups in Papua New Guinea. AJPA, 23:363-380.
   (ref.7) Hill, A.V.S. et al. (1987) Ahaptoglobinaemia in Melanesia: DNA and malarial antibody studies. Trans. R. Soc. Trop. Med. Hyg., 81:573-577.
6. ahaptoglobinemia as an indicator of malarial infection
   (ref.8) Rougemont, A. {\em et al}. (1988) Hypohaptoglobinaemia as an epidemiological and clinical indicator for malaria. Lancet, 709-712.